ILÚM helps to meet the infectious disease challenge

Infectious diseases are a significant burden
for patients and hospitals alike

Infectious diseases are extremely taxing on hospital systems, healthcare professionals, and patients. Of this massive burden, sepsis is one of the most deadly and costly manifestations.

Approximately 1 out of every 2 hospitalized patients is administered at least 1 antibiotic.1 Much of this is inappropriate use and leads to additional costs and the risk of adverse events.2

Sepsis is the most expensive condition to treat in US hospitals, at an average cost of $21,000 per case—with the cost of severe sepsis averaging $38,000 per case.3 28% to 50% of people who get sepsis will die.4

Evidence-based clinical treatment pathways are critical for infectious disease management

Hospitals that follow evidence-based treatment guidelines have demonstrated positive outcomes, including5,6:

  • Reduced mortality
  • Shorter length of stay
  • Fewer unnecessary days of therapy

Variability in patient care is a significant problem

Despite hospital clinical pathways, adherence rates to evidence-based guidelines for infectious disease remain highly variable7

  • Inappropriate use of empiric antibiotics is common in US hospitals and is associated with an increased 30-day mortality rate8
  • Evidence suggests that redundant coverage with antibiotics was seen in 78% of US hospitals, increasing costs and the risk for adverse drug effects2

Updated standards and measures are changing the way you operate

The requirements from organizations like the Joint Commission and CMS for ID, stewardship, and sepsis are constantly evolving.9 An integrated data system solution can help you stay ahead.

The Joint Commission's requirements on stewardship now include9:

  • Implementation of action steps to enable key stewardship interventions, such as systemic evaluation of ongoing treatment need, after a set period of initial treatment
  • Utilization of clinical protocols promoting evidence-based prescribing
  • Initiation of reporting to track progress toward key AMS metrics and delivery to stakeholders.  This includes information about antimicrobial prescribing levels and resistance rates

CMS requirements on sepsis management now include10:

  • Clear definitions for more advanced presentations, such as severe sepsis and septic shock
  • Strict compliance requirements (all or nothing) within a tight timeframe
    • For severe sepsis: serum lactate measurement, blood cultures, and antibiotics within 3 hours; repeat serum lactate within 6 hours
    • For septic shock: serum lactate, blood cultures, antibiotics, and resuscitation fluids within 3 hours; repeat volume status, perfusion assessment, and vasopressors within 6 hours

The ILÚM Solution

ILÚM Insight-ID can help address the challenges of infectious diseases with data-driven capabilities that enhance patient care and optimize program performance.

Learn More

Reference: 1. Magill SS, Edwards JR, Beldavs ZG, et al. Prevalence of antimicrobial use in US acute care hospitals, May-September 2011. JAMA. 2014;312(14):1438-1446. doi:10.1001/jama.2014.12923. 2. Schultz L, Lowe TJ, Srinivasan A, Neilson D, Pugliese G. Economic impact of redundant antimicrobial therapy in US hospitals. Infect Control Hosp Epidemiol. 2014;35(10):1229–1235. doi:10.1086/678066. 3. Tiru B, DiNino EK, Orenstein A, et al. The economic and humanistic burden of severe sepsis. PharmacoEconomics. 2015;33:925–937. 4. Wood KA, Angus DC. Pharmacoeconomic implications of new therapies in sepsis. PharmacoEconomics. 2004;22(14):895-906. 5. Hecker MT, Fox CJ, Son AH, et al. Effect of a stewardship intervention on adherence to uncomplicated cystitis and pyelonephritis guidelines in an emergency department setting. PLoS One. 2014;9(2):e87899. doi:10.137/journal.pone.0087899. 6. Johnstone J, Mandell L. Guidelines and quality measures: do they improve outcomes of patients with community-acquired pneumonia? Infect Dis Clin North Am. 2013;27(1):71–86. doi:10.1016/j.idc.2012.11.001. 7. Ebben RHA, Vloet LCM, Verhofstad MHJ, Meijer S, Mintjes-de Groot JAJ, van Achterberg T. Adherence to guidelines and protocols in the prehospital and emergency care setting: a systematic review. Scand J Trauma Resusc Emerg Med. 2013;21:9. doi:10.1186/1757-7241-21-9. 8. Marquet K, Liesenborgs A, Bergs J, Vleugels A, Claes N. Incidence and outcome of inappropriate in-hospital empiric antibiotics for severe infection: a systematic review and meta-analysis. Crit Care. 2015;19:63. doi:10.1186/s13054-015-0795-y. 9. The Joint Commission. Approved: new antimicrobial stewardship standard. Joint Commission Perspectives. 2016;36(7):1-8. 10. American College of Emergency Physicians. Sepsis CMS Core Measure (SEP-1) Highlights. Available at: Accessed December 7, 2016.